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Monday 2 July 2018

Monday 02 Jul

09:00

Plenary session: Translational mycology / From laboratory discovery to patient care

Donald Sheppard, Canada

10:00

Break

10:30

Parallel session IV

Parallel session IV will take place from 10:30 hrs. until 12:00 hrs. and consists of six symposia.

S4.1 Molecular and cell biology of fungal pathogens

Convener: Neil Gow, United Kingdom

10:30

S4.1a The cell biology of cell walls of fungal pathogens and the interaction with immune cells

Neil Gow, United Kingdom

10:55

S4.1b Cell biology and structure of the Candida cell wall

Megan Lenardon, Australia

11:20

S4.1c Haploid Candida albicans as a powerful tool for new discoveries

Yue Wang, Singapore

11:45

S4.1d Dysfunction in complex I of Candida albicans influences the phagocytosis and killing ability of macrophage and colonization in mice intestine

Xiaodong She, China

S4.2 Cryptococcal meningitis clinical trials

Convener: Tihana Bicanic, United Kingdom

10:30

S4.2a ACTA and beyond

Thomas Harrison, United Kingdom

10:55

S4.2b New and novel agents for prevention of cryptococcal disease

David Boulware, USA

11:20

S4.2c AmBition-CM: High dose Liposomal Amphotericin for HIV related cryptococcal meningitis

William Hope, United Kingdom

11:45

S4.2d Dynamic ploidy changes drive emergence of fluconazole resistance in human cryptococcal meningitis

Neil Stone, United Kingdom

S4.3 Antifungals Pipeline session

10:30

S4.3a CD101 – Cidara

Taylor Sandison, USA

10:55

S4.3b F901318 - F2G

John Rex, United Kingdom

11:20

S4.3c SCY-078 - Scynexis

David Angulo, USA

11:45

S4.3d VT-1598 - Viamet

Ed Garvey, USA

S4.4 Invasive infections in Asia

Conveners: Arunaloke Chakrabarti, India & Ruo-yu Li, China

10:30

S4.4a The unique features and challenges of yeast infections in Asia: focus on Candida tropicalis

Yee-Chun Chen, Taiwan

10:55

S4.4b Black mycelial fungal infection with special reference to Cladophialophora bantiana - Asian perspectives

Retno Wahyuningsih, Indonesia

11:20

S4.4c How to guard the mimic fungal infection in Asia?

Ariya Chindamporn, Thailand

11:45

S4.4d Fereydounia khargensis, an emerging Ustilaginomycetous opportunistic yeast, and antifungal resistances

R. Mohdtap, Malaysia

S4.5 New insights in the management of invasive fungal disease in haematology

Convener: Peter Donnelly, the Netherlands

10:30

S4.5a Invasive aspergillosis: New risk groups

Livio Pagano, Italy

10:55

S4.5b New management strategies (EORTC study)

Peter Donnelly, the Netherlands

11:20

S4.5c New antifungals (isavuconazole, new formulations of posaconazole, drugs in the pipeline)

Johan Maertens, Belgium

11:45

S4.5d New guidelines (ECCMID Aspergillus, IDSA Aspergillus and ECIL2017)

Fanny Lanternier, France

S4.6 MMCR case report session

Convener: Oliver Kurzai, Germany & Katrien Lagrou, Belgium

10:30

S4.6a Case 1

Shivaprakash Rudramurthy, India

10:55

S4.6b Case 2

Jochem Buil, the Netherlands

11:45

S.4.6c Case 3

Rachel Caligiorne, Brazil

12:00

Lunch break

Poster Pitch session III

12:15 - 13:15hrs (Ruby loung, first floor)

13:30

Plenary session: Clinically validation and implementation of next generation sequencing into a clinical laboratory for patient care testing

Sean Zhang, USA

14:30

Break

15:00

Plenary session V

Parallel session V will take place from 15:00 hrs. until 16:30 hrs. and consists of six symposia.

S5.1 Hot topics in Taxonomy – Can we define fungal species borders?

Convener: June Kwon-Chung, USA

15:00

S5.1a Viewing species complexes through a phylogenomic lens – the Curious Case of Cryptococcus

David Engelthaler, USA

15:25

S5.1b What should be the ideal criteria for species delimitation in pathogenic fungi?

John Taylor, USA

15:50

S5.1c Mitochondrial genomes and species boundaries in the genus Fusarium

Balász Brankovics, the Netherlands

16:15

S5.1d Evolution of virulence genes and cryptic speciation in the fungal pathogen Histoplasma 

Victoria Sepúlveda, USA

S5.2 Superficial dermatophytes

Conveners: Ryoji Tsuboi, Japan & Ruoyu Li, China

15:00

S5.2a Epidemiology and clinical implication of dermatophytes and nondermatophytes in South East Asia

Sumanas Bunyaratavej & Charussri Leeyaphan, Thailand

15:25

S5.2b Cutaneous infection by zoonotic dermatophytes: an update

Pei-lun Sun, Taiwan

15:50

S5.2c Molecular epidemiology of dermatophytes

Mochizuki Takashi, Japan

16:15

S5.2d New oral and topical treatments for onychomycosis

Ryoji Tsuboi, Japan

S5.3 Beyond antifungal / host directed therapy

Convener: Mihai Netea, the Netherlands

15:25

S5.3a Host-directed therapy in candidemia

Mihai Netea, the Netherlands

15:25

S5.3b New insights in diagnosis and immunopathology of aspergillosis

Agostinho Carvalho, Portugal

15:50

S5.3c New insights in Cryptococcus infections

Robin May, United Kingdom

16:15

S5.3d Quantifying host-pathogen interaction in blood from patients with selected immunodeficiencies

Kerstin Hünniger, Germany

S5.4 Mucoralean infections

Convener: Anna Skiada, Greece

15:00

S5.4a Managing mucormycosis: why is it so difficult? 

Ashraf Ibrahim, USA

15:25

S5.4b Diagnostics: From histopathology and cultures to qPCR and

Birgit Willinger, Austria

15:50

S5.4c Challenging Cases of Mucormycosis

Rajeev Soman, India

16:15

S5.4d Mucormycosis in patients with hematological diseases after hematopoietic stem cell transplantation and chemotherapy

Yuliya Rogacheva, Russia

S5.5 From Basic Science to Patient Care

Convener: Dieter Buchheidt (DMykG), NN (NVMy)

15:00

S5.5a Translating antifungal immunology into patient care

Frank van de Veerdonk, the Netherlands

15:30

S5.5b Translating mycology into patient care

Oliver Kurzai, Germany

16:00

S5.5c Clinical challenges in the management of invasive fungal infections

Andreas Groll, Germany

16:15

S5.5d Candida auris: understanding the mechanisms of host immune response

Mariolina Bruno, the Netherlands

S5.6 ISHAM Working Group: Fusarium

Conveners: Anne van Diepeningen & Abdullah Al-Hatmi, the Netherlands

15:00

S5.6a The trans-kingdom pathogen Fusarium

Anne van Diepeningen, the Netherlands

15:25

S5.6b Fusarium keratitis: the species and their occurrence

Grit Walther, Germany

15:50

S5.6c Intrinsic resistance to antifungals

Joseph Meletiadis, Greece

16:15

5.6d Histological characterization and host response during Fusarium solani infection in an ex-vivo human skin model

Dora Corzo-Leon, United Kingdom

16:30

Parallel session VI

Parallel session VI will take place from 16:30 hrs. until 18:00 hrs. and consists of six symposia.

S6.1 Functional genomics and systems biology

Convener: Berhard Hube, Germany

16:30

S6.1a QPCR detection of Mucorales DNA in bronchoalveolar lavage fluid for pulmonary mucormycosis diagnosis

Laurence Millon, France

16:55

S6.1b The relevance of β subunit of F1Fo-ATP synthase to Candida albicans lethality by affecting carbon flexibility

Shuixiu Li, China

17:20

S6.1c Candida spp. functional genomics

Geraldine Butler, Ireland

17:45

S6.1d Comparative genomics for understanding the development of multidrug resistance in Candida lusitaniae

Dominique Sanglard, Switzerland

S6.2 ABPA

Convener: Ritesh Agarwal, India

16:30

S6.2a Recent advances in allergic bronchopulmonary aspergillosis complicating asthma

Arunaloke Chakrabarti, India

16:30

S6.2b Severe asthma with fungal sensitization

David Denning, United Kingdom

17:20

S6.2c Recent advances in allergic bronchopulmonary aspergillosis complicating cystic fibrosis

Richard Moss, USA

17:45

S6.2d A new Aspergillus fumigatus Western Blot assay for IgE sensitization and Allergic Broncho Pulmonary Aspergillosis diagnosis

Raphael Piarroux, France

S6.3 Tropical implantation diseases

Convener: Flavio Queiroz-Telles, Brazil

16:30

S6.3a Management of chromoblastomycosis : difficulties, challenges and perspectives in developing countries

Flavio Queiroz-Telles, Brazil

16:55

S6.3b The expanding cat-transmmited sporotrichosis in Brazil

Anderson Rodrigues, Brazil

17:20

S6.3c Diversity among coelomycetous isolates from cutaneous and subcutaneous infections

Dea Garcia-Hermoso, France

17:45

S6.3d Conidiobolomycosis: presentation of two cases in adult and infant

Alexandro Bonifaz, Mexico

S6.4 Aspergillus terreus frontline

Convener: Cornelia Lass-Floerl, Austria

16:30

S6.4a The Aspergillus terreus species complex: What is new

Jesus Guinea, Spain

16:55

S6.4b Outcome and treatment of Aspergillus terreus infections

Oliver Cornely, Germany

17:20

S6.4c Amphotericin B Resistance: New insights

Cornelia Lass-Flörl, Austria

17:45

S6.4d Molecular epidemiology and antifungal susceptibility profiles of Aspergillus terreus in Iran

Afsane Vaezi, Iran

S6.5 Malassezia in humans and animals

Conveners: Jacques Guillot, France & Teun Boekhout, the Netherlands

16:30

S6.5a Analysis of Malassezia microbiota in humans and animals: does it really help us to better understand and control Malassezia-related diseases?

Jacques Guillot, France

16:55

S6.5b The human skin microbiome: cause or effect? The role of Malassezia in human skin health and disease.

Thomas Dawson, Singapore

17:20

S6.5c The overgrowth of Malassezia spp.in canine atopic dermatitis - the reason or the result of disease?

Bozena Dworecka-Kaszak, Poland

17:45

S6.5d Characterization of growth of lipid-dependent Malassezia yeast species, members of the skin mycobiome

Hans de Cock, the Netherlands

S6.6 Surveillance azole resistance

Convener: Jacques Meis, the Netherlands

16:30

S6.6a Surveillance of azole resistance in Colombia

Patrice le Pape, France

16:55

S6.6b Surveillance and status quo of azole resistant Aspergillus in East Asia

Chi-Jung Wu,Taiwan

17:20

S6.6c First report of azole-resistant Aspergillus fumigatus harboring TR34/L98H and M220R in Brazil

Laura Bedin Denardi, Brazil

17:45

S6.6d The present status and surveillance of azole resistance in North America

Elizabeth Berkow, USA

18:00

Poster Pitch Session IV

19:00

Young ISHAM Evening

20:00

Spanish Speaking ISHAM/ECMM/GAFFI meeting Middle- and Latin America (Mexico, Colombia, Chile, Argentina, Ecuador, Uruguay, Venezuela…)

All ISHAM participants from the respective countries targeted by these outreach efforts would receive personal invitations to the respective evenings.

Monday 02 Jul

Poster Pitch session III

Poster Terminal 1

12:15

PP3.017 - ZnO nanoparticles coated by Chitosan-Linoleic acid inhibit the Candida growth and Biofilm formation in vitro

M. Roudbary, India

12:22

PP3.018 - AtrR, an essential regulator of azole resistance in Aspergillus fumigatus, acts via the TR34 element in the cyp51A promoter

Scott Moye-Rowley, USA

12:29

PP3.019 - Aspergillus fumigatus strains are adapted to the lung environment in a case of chronic pulmonary aspergillosis

Sara Gogo, United Kingdom

12:36

PP3.020 - Antifungal Activity and Cytotoxic Effect of Echinophora Extract, Carvacrol and Drug Caspofungin on Vaginal Candida albicans Infections on Cervical Cancer

Mohammad Yadegari, Iran

12:43

PP3.021 - Environmentally acquired mutations in Aspergillus fumigatus leading to azole resistance: An Asian situation

Yubhisha Dabas, India

12:50

PP3.022 - Concomitant isolation of Aspergillus species and Mycobacterium species in respiratory tract of patients: an underestimated microbial interaction?

Sarah Dellière, France

12:57

PP3.023 - Posaconazole tablet therapeutic drug monitoring in patients with chronic pulmonary aspergillosis

Chris Kosmidis, United Kingdom

13:04

PP3.024 - Aspergillus fumigatus fumagillin as possible virulence factor

Xabier Guruceaga, Spain

Poster Terminal 2

12:15

PP3.057 - Multiplex qPCR for rapid identification of Candida auris, C. haemulonii, C. duobushaemulonii and C. pseudohaemulonii

Amir Arastehfar, the Netherlands

12:22

PP3.058 - Comparative virulence of Candida auris with Candida haemulonii, Candida glabrata and Candida albicans in a murine model

Hamed Fakhim, Iran

12:29

PP3.059 - CoERG11 A395T mutation confers azole resistance in Candida orthopsilosis clinical isolates

Cosmeri Rizzato, Italy

12:36

PP3.060 - Severe recurrent vulvovaginal Candidiasis caused by mixed Candida species

Mohammad Effat, Egypt

12:43

PP3.061 - Optimization and application of fluorescent proteins in super-resolution microscopy of Candida albicans

Wouter Van Genechten, Belgium

12:50

PP3.062 - Ca37 monoclonal antibody inhibits Candida albicans growth in vitro and in vivo

Aitziber Antoran, Spain

12:57

PP3.063 - Activity of investigational tetrazole antifungals VT-1161 and VT-1598 against a collection of clinical Candida tropicalis isolates with reduced fluconazole susceptibility

Jeffrey Rybak, USA

13:04

PP3.064 - Isolates of Candida glabrata from the United States are enriched for specific sequence types with distinct MSH2 alleles

Keley Healey, USA

Poster Terminal 4

12:15

PP3.097 - Development of echinocandin resistance after in vitro micafungin exposure in clinical isolates of Candida glabrata

Olga Rivero-Menendez, Spain

12:22

PP3.098 - Mechanisms of invisibility: 3D, real time and holographic imaging reveals dynamics of Candida albicans evasion of host recognition

June Bain, Spain

12:29

PP3.099 - Photodynamic inactivation can fight biofilms of Candida albicans strains with constitutive efflux

Helena Bujdáková, Slovak Republic

12:36

PP3.100 - In vitro study of photodynamic inactivation against Fonsecaea monophora and the application of ALA-APDT on refractory Chromoblastomycosis

Liyan Xi, China

12:43

PP3.101 - Restoration Melanin of Fonseace monophora reduced Its Pathogenicity to Galleria mellonella

Yinghui Liu, China

12:50

PP3.102 - High-throughput RNA sequencing (RNA-seq) analysis of macrophages infected with Fonsecaea monophora

Junmin Zhang China

12:57

PP3.103 - Fungal eye infections among ophthalmologic patients at ABSUTH, Aba, Abia State, Nigeria

Ada Ngwogu, Nigeria

13:04

PP3.104 - The pattern of fungal infection in Isfahan, Iran

Asghar Heidarian, Iran

Poster Terminal 5

12:15

PP3.137 - In vitro inducing conditions to promote titan-like cells formation in C. neoformans

Rocio García-Rodas, Spain

12:22

PP3.138 - Novel Dermatophytes from Indian soils

Rahul Sharma, India

12:29

PP3.139 - In vitro and in vivo efficacy and toxicity of nonyl 3,4-dihydroxybenzoate, a potent compound against dermatophytes biofilms

Caroline Costa-Orlandi, Brazil

12:36

PP3.140 - New and emerging zoophilic dermatophytes in Europe

Adela Cmoková, Czech Republic

12:43

PP3.141 - Emergence of Trichophyton benhamiae in guinea pigs: a retrospective study from the mycology laboratory of the veterinary college of Alfort

Jacques Guillot, France

12:50

PP3.142 - Molecular epidemiology of Trichophyton mentagrophytes – a new approach

Silke Uhrlass, Germany

12:57

PP3.143 - A national survey on Tinea capitis in France: epidemiology and diagnostic procedures

Jean-Pierre Gangneux, France

13:04

PP3.144 - Place of Trichophyton soudanense in the Trichophyton rubrum complex: a clinical isolates analysis

Maud Gits-Muselli, France

Poster Terminal 6

12:15

PP3.177 - Conductivity: A novel approach for antifungal susceptibility testing

Srivastava Neelabh, India

12:22

PP3.178 - Interactions with fungal cell wall polysaccharides determines the salt tolerance of antifungal plant defensins

Mark Bleackley, Australia

12:29

PP3.179 - The plant defensin HXP124 has the potential to be a new safe and effective topical treatment for onychomycosis

Nicole Van der Weerden, Australia

12:36

PP3.180 - The antifungal mechanism of action for plant defensins is defined via treatment of a barcoded yeast deletion libraryf

Kathy Parisi, Australia

12:43

PP3.181 - Fungal study of guano bat samples

Cristine Goebel, Brazil

12:50

PP3.183 - Impaired phagocytosis directs human monocyte activation in response to fungal derived ß-glucan particles

Jessica Quintin, Brazil

12:57

PP3.184 - Cutaneous infection caused by Fusarium lichenicola in a patient with verrucous hyperplasia vermiculatum manifestation

Sha Lu, China

Poster Terminal 8

12:15

PP3.217 - Genome mining and transcriptomic analysis of iron metabolism genes in Scedosporium apiospermum

Yohann Le Govic, France

12:22

PP3.218 - Production of Scedosporium boydii CatA1 and SodC recombinant proteins: another step towards a standardized test for serodiagnosis of Scedosporium infections

Sara Mina, Lebanon

12:29

PP3.219 - Hybrid histidine kinase III: new therapeutic target for Scedosporium apiospermum?

Anaïs Hérivaux, France

12:36

PP3.220 - Lignin degradation pathway in Scedosporium species

Wilfried Poirier, France

Monday 02 Jul

Poster Pitch session IV

Poster Terminal 1

18:00

PP4.025 - Molecular identification and antifungal susceptibility testing of fungal agents isolated from patients with idiopathic pulmonary fibrosis(IPF) in Tehran, Iran

M. Roudbary, India

18:07

PP4.026 - Isolation of Aspergillus species in respiratory specimens from adult patients with acute exacerbation of non-cystic fibrosis bronchiectasis; Data from Pakistan

Kauser Jabeen, Pakistan

18:14

PP4.02 - Azole resistance in Aspergillus fumigatus. Frequency and distributions of mutations in a tertiary center in the Netherlands

Jochem Buil, the Netherlands

18:21

PP4.028 - Development and multicentre evaluation of a screening method for echinocandin susceptibility testing of Aspergillus spp.

Joseph Meletiadis, Greece

18:28

PP4.029 - Molecular identification and antifungal susceptibility patterns of invasive Aspergillus species following CLSI and EUCAST guidelines

Yubhisha Dabas, India

18:35

PP4.030 - The IL17RA and CARD10 genes are important in controlling Aspergillus fumigatus colonisation of the lung in allergic bronchopulmonary aspergillosis

Sara Gogo, United Kingdom

18:42

PP4.031 - Composting as a resource for environmental azole resistance mutation in Aspergillus fumigatus in Iran

Bita Mousavi, France

18:49

PP4.032 - Overexpression of cyp51A and cyp51b contribute to triazole resistance in clinical isolates of Aspergillus fumigatus from the United States

Jeffrey Rybak, USA

Poster Terminal 2

18:00

PP4.065 - Modulation of Candida albicans infection by the non-selective muscarinic receptor agonist pilocarpine hydrochloride

Christopher Nile, United Kingdom

18:07

PP4.066 - Do Candida albicans biofilms contain persister cells?

Iryna Denega, France

18:14

PP4.067 - Identification of recessive lethal alleles in the Candida albicans genome: a constraint on loss-of-heterozygosity events in this species

Melanie Legrand, France

18:21

PP4.068 - Healthcare linen as a source of a mucormycosis case cluster that involved different sites of infection and different Mucorales species

Hong Nguyen, USA

18:28

PP4.069 - Genetically closely related azole-resistant Candida tropicalis in environments can be a threat to healthcare

Zi-Li Zhou, Taiwan

18:35

PP4.070 - Mapping the interaction of the Candida albicans multidrug resistance ABC protein Cdr1 with pump inhibitor clorgyline that stimulates ATPase activity

Masakazu Niimi, Thailand

18:42

PP4.071 - Metabolic adaptation triggers Candida albicans biofilm phenotype

Gordon Ramage, United Kingdom

18:49

PP4.072 - The use of long and short-read sequencing technology to elucidate genomic variation and epidemiology of Candida glabrata in North America

R.M. Welsh, USA

Poster Terminal 4

18:00

PP4.105 - YEAST PANEL Multiplex PCR Assay for Identification of Invasive Yeast Pathogens: Novel Diagnostic Strategy, Useful for Developing Countries

Amir Arastehfar, the Netherlands

18:07

PP4.106 - Increasing trend of mucormycosis mixed with other invasive mycoses from a tertiary care centre in north India

Jagdish Chander, India

18:14

PP4.107 - Invasive fungal diseases in patients with acute leukemia or allogeneic stem cell transplantion recepients: A prospective multicenter observational study

Gokhan Metan, Turkey

18:21

PP4.108 - A genetic and genomics approach identifies novel pathways of human antifungal immune responses

Vinod Kumar Magadi Gopalaiah, the Netherlands

18:28

PP4.109 - Epidemiology of fungaemia and fungal meningitis in Sweden: a nationwide retrospective observational survey from sept 2015-aug 2016

Lena Klingspor, Sweden

18:35

PP4.110 - Comparative sequencing of ITS and D1/D2 domains of ribosomal DNA for Molecular discrimination of fungal moulds

Baskar Raju, India

18:42

PP4.111 - Molecular diagnostics of arthroconidial yeasts– frequent pulmonary opportunists

Engin Kaplan, Turkey

18:49

PP4.112 - Neglected diseases in Nigerians, diagnostics challenges: Invasive Fungal Infections

Rita Oladele, Nigeria

Poster Terminal 5

18:00

PP4.145 - Prevalence and virulence of the zoophilic dermatophyte Trichophyton benhamiae

Yvonne Gräser, Germany

18:07

PP4.146 - Epidemiology of dermatophytosis in the Caribbean

Harish Gugnani, India

18:14

PP4.148 - Long-term practice of animal vaccination against dermatophytosis

Marina Manoyan, Russia

18:21

PP4.150 - A Holistic Approach to the Mycetoma Management

A.H. Fahal, Sudan

18:28

PP4.151 - Application of real-time PCR assays for the diagnosis of histoplasmosis using three molecular targets in human FFPE tissues and whole-blood

Beatriz Lucia Gomez, Colombia

18:35

PP4.152 - Metagenomic analysis of environmental samples from mycetoma endemic area in Sudan

S.M. Bakhiet, Sudan

Poster Terminal 6

18:00

PP4.185 - Topical use of 1% luliconazole cream cured with Fusarium oxysporum infected refractory ulcers on an elderly patient’s leg and ankle

Xin Ran, China

18:07

PP4.186 - Primary cutaneous Fusarium solani infection in a hemodialysis patient

Dongmei Shi, China

18:14

PP4.187 - Biological activity of lipids extracted from two isolates of Fusarium oxysporum (environmental and clinical) in Galleria mellonella

Pedronel Araque, Colombia

18:21

PP4.188 - Diversity of clinically relevant Fusarium species complexes: preliminary analysis of from an 11-yr prospective surveillance in France

Dea Garcia-Hermoso, France

18:28

PP4.189 - Epidemiology and in vitro susceptibility of Fusarium species from human infections in Germany – results of a retrospective multicenter study

Axel Hamprecht, Germany

18:35

PP4.190 - Type 17 immunity controls Malassezia skin infection

Florian Sparber, Switzerland

18:42

PP4.191 - A rapid molecular assay for direct quantification of Malassezia pachydermatis in otic swabs

Gemma Castellá, Spain

18:49

PP4.192 - 'PepBiotics', novel antimicrobial peptides to fight fungal infections caused by Aspergillus fumigatus and Malassezia furfur

Hans De Cock, the Netherlands